Cell Disruption
Unlocking Microbial Protein Sources
Microorganisms such as yeasts, bacteria, and algae are nutritional powerhouses. In addition to proteins, they contain vitamins, enzymes, and other bioactive compounds of high interest to the food and nutraceutical industries. To make these valuable ingredients available, their cell structures must be broken down efficiently and precisely.
NETZSCH has decades of experience in wet grinding and offers specially optimized agitator bead mills for cell disruption. These systems generate high shear forces under controlled process conditions – ideal for the gentle yet effective breakdown of microorganisms.
By precisely controlling temperature, energy input, and grinding media load, target substances can be released efficiently without denaturation. The systems are flexibly scalable – from lab equipment for product development to full-scale production lines. Complemented by suitable mixing and separation technologies, NETZSCH offers complete process solutions from a single source – tailored to your raw materials, your target products, and your production goals.
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Application Example
Cell Disruption of Yeast Cells
At NETZSCH, yeast cell disruption refers to the process of opening the outer cell walls or membranes of yeast cells to access intracellular components such as proteins, nucleic acids, enzymes, and other valuable molecules. NETZSCH agitator bead mills play a key role in this process by enabling precise, efficient, and reproducible cell disruption – a crucial step in microbiological research, diagnostic applications, and biotechnology.
Where are yeast-derived proteins used in the food industry?
- Natural bio-emulsifiers
- Stabilizers
- Poultry feed (preferred over plant-based sources due to higher vitamin B content)
- Dietary products
- Bread and baked goods
- Protein bars and sports nutrition
- Weight management food products
Cell Disruption of Algae Cells
Algae – those microscopic powerhouses – are an abundant and renewable source of valuable nutrients. Unlocking their full potential requires targeted cell disruption, a process that breaks down cell walls or membranes to release proteins, pigments, lipids, and oils. At NETZSCH, numerous successful trials have been conducted in recent years with leading companies and research institutions using agitator bead mills and the Economic Dispersionizer Omega®.
Where are algae-derived ingredients used?
- Biofuels
- High-value bioproducts and dietary supplements
- Advanced pharmaceutical formulations
- Nutrient-rich feed for aquaculture and animal nutrition
Intact Proteins
Effective Cell Disruption
High Scalability
Hygienic Design
High Process Efficiency
Gentle Temperature
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Application Literature
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