Pharma Seminar
Micronization and Nanonization of Pharmaceutical Substances
The majority of approved pharmaceutical substances exhibit poor solubility in the human body. By reducing the particle size and thereby increasing the surface area of the active ingredient particles, the dissolution rate and thus the bio-availability can be significantly increased.
This then means that the same effect can be achieved with smaller amounts of active substance, but with fewer side effects. In the pharmaceutical industry, terms for comminution such as micronization and nanoization have become established. Agitator bead mills are primarily used for the process of wet grinding. The costs for the development of a suitable formulation for new products or a production method for generics are primarily driven and determined by the price of the active ingredient itself. A reduction of the development costs can be achieved through a deep understanding of the effect of different process parameters.
In the „Micronization and Nanonization of Pharmaceutical Substances“ seminar, the essential operating parameters will be discussed and presented in a logical context. Possible solutions for process optimization will be shown. The process will be considered holistically, from cleaning and sterilization to predispersion and micronization, through to bottling. It will then be shown how a process developed on a laboratory scale can be transposed to an actual production scale.
Target Group
- Research and Development
- Process Design
- As well as operators of machines already in operation
Content of the Seminar
- Presentation of the Business Unit NETZSCH Grinding & Dispersing
- Characterizing the success of the comminution
- Terms and definition
- Overview of the grinding media-free dispersion systems – mixing, wetting and dispersing
- Overview of NETZSCH grinding systems, agitator bead mills
- Effect of different process parameters
- Model of the load energy and the number of impacts
- Effect of the dwell time distribution
- Grinding media selection and scale-up
- Calculation – from laboratory to production scale
- Limits of wet grinding
- True comminution and gentle dispersion
- Discussion
Seminar Information
- Duration of the course: 2 days
- Attendance: approx. 10
- Course charge contains: 2 overnight stays with breakfast Catering during the event Lunch / dinner
- Seminar documents Fee: EUR 1,500.00 + VAT
Downloads
General Information
Please use the appropriate registration form. The registrations will be handled in order of date of receipt.
Some days after registration, you will receive a confirmation. Shortly before the event, you will receive a description of how to reach the venue and - depending on the type of the event - a reservation confirmation for your hotel room.
For customers inside the EC: Please do always tell us your value added tax identification number.
| Venue in Selb: | Venue in Hanau: | Venue in China |
|---|---|---|
| NETZSCH-Feinmahltechnik GmbH Sedanstraße 70 95100 Selb Germany | NETZSCH Trockenmahltechnik GmbH Rodenbacher Chaussee 1 63457 Hanau Germany | NETZSCH (Shanghai) Machinery and Instruments Co., Ltd. No.3136, Jia’an Road, Jiading, Shanghai 201814 P. R. China |
In general, the accommodation costs are included in the course fee.
However, if they are not included, we request you to kindly pay for your hotel room when you check out.
For all the courses we offer, we have a certain number of rooms available at the location of the event or in close proximity. We would be happy to reserve a room for you at one of these hotels. For this purpose we require your date of arrival and departure.
Peu avant la fin des cours et séminaires ou des formations individuelles, vous recevrez une facture qui sera envoyée à l'adresse de facturation que vous nous avez communiquée. Si vous ne nous communiquez pas d'adresse de facturation, la facture sera envoyée directement au participant au séminaire. Pour les séminaires qui ont lieu en Allemagne, le taux de TVA en vigueur (actuellement 19 %) sera appliqué. (Exception : les clients de l'UE disposant d'un numéro de TVA)
The registration can be cancelled free-of-charge up to 14 days before the start of the event. If we receive cancellation at a later date, then any hotel costs incurred will be charged.
We require written cancellation. Surrogate participants are accepted.
If the program of the event is not available as a download on our website, then each participant will receive a complete event schedule by fax or e-mail shortly before the event.
We reserve the right to modify the schedule/program.
NETZSCH-Feinmahltechnik GmbH and NETZSCH Trockenmahltechnik GmbH reserve the right to cancel planned events up until one week before they begin. Should this be the case, affected participants will be informed immediately. NETZSCH-Feinmahltechnik GmbH and NETZSCH Trockenmahltechnik GmbH will not be liable for compensation for damages.
Any training documents and lists of participants from our events are only intended for the personal use of the participants. A duplication or disclosure of these documents to third persons is not allowed.